Catherine Grosdemange-Billiard
Professor
E-mail: grosdemange@chimie.u-strasbg.fr
Office: Université de Strasbourg (UdS), Institut Le Bel
Biography
Education:
1980- Maîtrise de Chimie, Université de Reims-Champagne-Ardennes (URCA)
1981- DEA, Organic and Macromolecular Synthesis, Université de Lille
1983- Doctorat, « Thermolysis of enaminoesters », URCA,
1985- Maîtrise de biologie humaine en cancérologie expérimentale, Université Paris V,
2002- Habilitation à diriger des recherches, Université Louis Pasteur (ULP)
1980- Maîtrise de Chimie, Université de Reims-Champagne-Ardennes (URCA)
1981- DEA, Organic and Macromolecular Synthesis, Université de Lille
1983- Doctorat, « Thermolysis of enaminoesters », URCA,
1985- Maîtrise de biologie humaine en cancérologie expérimentale, Université Paris V,
2002- Habilitation à diriger des recherches, Université Louis Pasteur (ULP)
Selected Publications
Synthesis of (3R, 4S)-3,4-dihydroxy-5-oxohexylphosphonic acid, an isosteric analogue of 1-deoxy-D-xylulose 5-phosphate substrate of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase. O. Meyer, C. Grosdemange-Billiard, D. Tritsch & M. Rohmer, Org. Biomol. Chem. 2003, 1, 4367-4372
Isoprenoid biosynthesis as a novel target for antibacterial and antiparasitic drugs. M. Rohmer, C. Grosdemange-Billiard, M. Seemann & D. Tritsch, Curr. Op. Investig. Drugs, 2004, 5 ; (2); 154-162.
(3R,4S)-3,4,5-Trihydroxy-4-methylpentylphosphonic acid, an isosteric phosphonate analogue of 2-C-methyl-D-erythritol 4-phosphate, a key intermediate in the new pathway for isoprenoid biosynthesis. G. Hirch, C. Grosdemange-Billiard, D. Tritsch & M. Rohmer, Tetrahedron Lett.. 2004, 45, 519-521.
Short and efficient synthesis of a stock material of dihydroxyacetonephosphate from glycidol. O. Meyer, M. Rohmer & C. Grosdemange-Billiard, Tetrahedron Lett.. 2004, 45, 7921- 7923.
Practical synthesis of 1-deoxy-D-xylulose and 1-deoxy-D-xylulose 5-phosphate allowing deuterium labelling. O. Meyer, J-F. Hoeffler, C. Grosdemange-Billiard & M. Rohmer, Tetrahedron 2004, 60, 12153-12162
Isoprenoid biosynthesis as target for antibacterial and antiparasitic drugs: phosphonohydroxamic acids as inhibitors of deoxyxylulose phosphate reducto-isomerase. L. Kuntz, D. Tritsch, C. Grosdemange-Billiard, A. Hemmerlin, A. Willem, T.J. Bach & M Rohmer, Biochem. J. 2005, 386, 127-135.
Lewis acid mediated regioselective ring opening of benzylglycidol with dibenzylphosphate: short and very efficient synthesis of dihydroxyacetone phosphate. O. Meyer, S. Ponnaire, M. Rohmer & C. Grosdemange-Billiard, Org. lett. 2006, 8, 4347-4350O.
Synthesis and activity of two trifluorinated analogues of 1-deoxy-D-xylulose 5-phosphate. O. Meyer, C. Grosdemange-Billiard, D. Tritsch & M. Rohmer, Tetrahedron Lett.. 2007, 48, 711-714
Isoprenoid biosynthesis as a novel target for antibacterial and antiparasitic drugs. M. Rohmer, C. Grosdemange-Billiard, M. Seemann & D. Tritsch, Curr. Op. Investig. Drugs, 2004, 5 ; (2); 154-162.
(3R,4S)-3,4,5-Trihydroxy-4-methylpentylphosphonic acid, an isosteric phosphonate analogue of 2-C-methyl-D-erythritol 4-phosphate, a key intermediate in the new pathway for isoprenoid biosynthesis. G. Hirch, C. Grosdemange-Billiard, D. Tritsch & M. Rohmer, Tetrahedron Lett.. 2004, 45, 519-521.
Short and efficient synthesis of a stock material of dihydroxyacetonephosphate from glycidol. O. Meyer, M. Rohmer & C. Grosdemange-Billiard, Tetrahedron Lett.. 2004, 45, 7921- 7923.
Practical synthesis of 1-deoxy-D-xylulose and 1-deoxy-D-xylulose 5-phosphate allowing deuterium labelling. O. Meyer, J-F. Hoeffler, C. Grosdemange-Billiard & M. Rohmer, Tetrahedron 2004, 60, 12153-12162
Isoprenoid biosynthesis as target for antibacterial and antiparasitic drugs: phosphonohydroxamic acids as inhibitors of deoxyxylulose phosphate reducto-isomerase. L. Kuntz, D. Tritsch, C. Grosdemange-Billiard, A. Hemmerlin, A. Willem, T.J. Bach & M Rohmer, Biochem. J. 2005, 386, 127-135.
Lewis acid mediated regioselective ring opening of benzylglycidol with dibenzylphosphate: short and very efficient synthesis of dihydroxyacetone phosphate. O. Meyer, S. Ponnaire, M. Rohmer & C. Grosdemange-Billiard, Org. lett. 2006, 8, 4347-4350O.
Synthesis and activity of two trifluorinated analogues of 1-deoxy-D-xylulose 5-phosphate. O. Meyer, C. Grosdemange-Billiard, D. Tritsch & M. Rohmer, Tetrahedron Lett.. 2007, 48, 711-714
This page was last updated Monday, October 26, 2009